Information on Tramadol

Tramadol (generic for Ultram) is a white, bitter, crystalline and odorless powder.
Each Tramadol tablet contains 50 mg of tramadol hydrochloride and is white in color.

HOW DOES Tramadol WORK?

Tramadol acts on the central nervous system and unlike codeine and its derivative medications is a totally synthetic analgesic compound.
Although its mode of action is not completely understood, from animal tests, at least two complementary mechanisms appear applicable: the binding of parent compound and its metabolite to opioid receptors and weak inhibition of reuptake of norepinephrine and serotonin by nerves located within the central nervous system.
Tramadol-induced analgesia is only partially reversed by the opiate antagonist naloxone in several animal tests.
Tramadol has been shown to inhibit reuptake of norepinephrine and serotonin in vitro.
These mechanisms may contribute independently to the overall analgesic profile of Tramadol.
Analgesia in humans begins approximately within one hour after administration and reaches a peak in approximately two to three hours...